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eHOMD database: Ref seq Aligned FASTA vs Full RefSeq?

I am working with 16S rRNA amplicon sequencing data (targeting the V3–V4) and would like to use the eHOMD database for taxonomic assignment. I noticed that eHOMD provides "Ref seq Aligned FASTA File " and full RefSeq Version of the database. Which version is more appropriate for 16S amplicon analysis?

homd database

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