What is a recommended maximum read depth threshold for DNA variant filtration, supported by scientific articles?
Hi. I'm searching for scientific articles investigating a question "What is the best maximum read depth threshold for filtering out false-positive variants?" Variants called from WES or targeted sequencing / gene panels, to be more specific. Could you please share articles on that matter?
It's not a big deal to find these recommendations, but I need them to be somewhat justified. That's why I need research articles.
I've searched with Google and Google Scholar, searched in PubMed - no luck. It would also be nice if you shared your article search strategies, since mine clearly failed.
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