GWAS for Klebsiella isolates
Hi guys,
I'm new to bioinformatics, but want to do GWAS on a group of Klebsiella blood culture isolates (roughly 50). I've been reading around this and just a bit confused how to determine how many control isolates (these would be non blood culture) I need. Basically looking for genomic characteristics that lend itself to invasiveness. I've seen some tools that can determine the control number - but it looks like I need to have tree files etc (ie already have sequenced my isolates) to figure out the control number. I would want to know the control number first preferably to determine feasibility.
Any help would be great.
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