ssGSEA cross-species
Hello, I am trying to implement a ssGSEA for a conserved list of genes. I want to be able to calculate an enrichment score that is comparable between 2 species (mouse and axolotl); comparing activity of a given pathway. If I run the analysis only on genes that have one-to-one orthologous mappings, would it be possible to obtain comparable metrics? I am running it on log-transformed kallisto-derived TPM.
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georgii.vdovin •
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