Hi everyone, I’ve just analyzed some 10x scRNA data using the mgatk tenx pipeline to gather information on a heteroplasmic variant of interest. I then applied t-SNE to observe the heteroplasmy variation across cells. I was wondering if the R Signac package, although designed for scATAC DNA, could still help me first define the heteroplasmic variant of interest and then assist with my subsequent needs on my scRNA data.

I was reading this: mito_stuartlab

I’d appreciate any advice. Thank you very much!