I have a SICER output file: island.bed which has 4 columns. I have to calculate z score for different histone modification files and see its density over certain regions in the genome. How can I do it?
I have .wig files for H3K9me3 ChIP and corresponding input samples. These are not library normalised and when uploaded on IGV, displays the absolute read …
I have generated 2 heatmaps using heatmap.2 function. Following is my command and it's output. First heatmap contains z-score which is been calculated by heatmap.2 …
Hello, I was viewing different methods for peak calling and came across two quite similar concepts but still different methods: MACS and [SICER][1]. The main …
Hi everyone, I'm new in ChiP-seq analysis. I'm using SICER to analyze histone modification data with a control library. I have some doubts regarding the …
my book chapter on ChIP-seq may help https://divingintogeneticsandgenomics.com/publication/2017-08-01-biostarhandbook/