HWE filter of vcf files
Hi
What is the appropriate approach to filter the snps(vcf format) with HWE parameter, Arlequin or vcftools. I've used vcftools for the advanced filer, like missing rate, MAF, etc. So i am wondering can i keep using it for the HWE. But i didn't see literatures using it instead they use Arlequin. So is it reliable using vcftools for HWE?
Thanks in advance
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lets start with: what are the purposes of filtering based on HWE in the first place? why are you doing it (specifically)?
filter the snps for the downstream analysis of population structure and genetics.