Hello all,
I'm interested in exploring smoking-induced mutations.
Therefore, I want to retrieve all the VCF files for lung cancer in smokers from the ICGC data portal.
However, I'm not sure if the information regrading the smoking status is restricted since I can't find it but I know it exists (see Alexandrov, Ludmil B., et al. "Mutational signatures associated with tobacco smoking in human cancer." Science 354.6312 (2016): 618-622.).
Does anyone have experience with analyzing that type of data?
And also, I was wondering if the VCF files can be found also for the hg38 genome and not only hg37? TIA