Need assistance in proper binding of cysteines
Hello!
I am newbie in protein building and i need to create disulfide bond between newly builded cysteine and another one to form active site for my ligand. Further i need to dock small molecule in this site.
Is there any tools to create such bond? Maybe MODELLER and it's model-disulfide.py script? Is CHIMERA and PyMOL editing not only visualization but coords in PDB file?
Thanks in advance!
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I think this should be possible with Chimera (although admittedly I never added this specific bond), a quick Google search showed me this tutorial. Probably section II will be of use for you?