Copy Number Analysis of Multiple Cohorts Using CNVkit
Hi everyone,
I am currently interested in performing combined analysis on WGS (Whole Genome Sequencing) data from four different cohorts. Some samples in these cohorts lack matched normal controls. I would like to inquire whether it is possible to create a pooled reference using normal samples from different cohorts and then proceed with copy number analysis.
Thank you for your assistance.
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rbioinfo •
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weisong •
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weisong •
1 answer
How about a human pangenome reference?
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rbioinfo •
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