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Prediction of altrered metabolites from altered gene expression

Dear all,

I have a list of diffrentially regulated genes from a single tissue. How can I obtain, or more precisely, predict, possibly affected metabolites?

I know about enrichment over metabolite databases, such as HMDB_Metabolites, Metabolomics Workbench Metabolites, and MetaboAnalyst (which needs both genes and metabolites so does not suit my need). I need more advanced/comprehensive tools, and preferably those methods that can use SBML metabolic data + information on DEGs and integrate them. Thank you in advance.

gene metabolites

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