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In silico evaluation of functional similarity across two sets of genes

Dear all,

I'd like to compare two sets of GO's, with potential repetitions (as the same GO can be attributed to multiple genes), to quantify the similarity of functional information across two lists of genes. How do you suggest to do it? Can you please recommend a method/program/package taking into consideration that multiple GOs can belong to the same gene and that multiple genes might have same GOs?

functional annotation go similarity

Yes, that's what I was searching for. Thanks

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