How to perform meta analysis for identification of heterogeneity between gene expression datasets
Hello all, I am performing a meta analysis of gene expression datasets to check for heterogeneity between the microarray datasets. What are the statistical tests we can perform for doing the same?
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What methods have you already considered or tried? If you are just getting started, the recommendation is to query 'meta-analysis statistics' in an online search engine or PubMed.
Thank you for replying to the question. I was thinking of performing Forests plot to identify the heterogeneity but was not sure if it is the right way. And after identifying a specific dataset as an outlier which might contribute to the heterogeneity do you think we should exclude that dataset?