We are analysing single cell RNA+proteom (CITE-seq) data.

One of the things we see - quite stable correlation between CD36 (protein) and S100A4 , S100A6 (rna).

Question: Any ideas/comments what might be the biological reason for such correlation ?

The data is from the recent Kaggle/NearIPS challenge "Open Problems - Multimodal Single-Cell Integration" https://www.kaggle.com/competitions/open-problems-multimodal

Anyone interested to participate/share experience/whatever with analysis of such single cell data - please let me know !

Here is some are correlations/feature importances S100A6 - light blue, S100A8 - light "red" - can be seen on top - by different methods