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SABDAB Blast database

Hello All,

This is all very new to me and I wanted to receive some input.

I would like to create a SABDAB database with the NCBI Blast image I currently have installed in one of my docker containers. My issue is that I downloaded the entire SABDAB database and noticed they are .PDB files. How would I convert these .pdb files to fasta to use with the makeblastdb from Blast? Or better yet, is this the right direction for creating a SABDAB blast database with Blast?

My thinking would be to convert these .pdb files to fasta. Then combine all these fasta files into one via cat command. From there use that file with the blast image.

blast fasta pdb ncbi sabdab

1 answer

My thinking would be to convert these .pdb files to fasta. Then combine all these fasta files into one via cat command. From there use that file with the blast image.

That should be fine. I noticed on SABDAB site that they are doing searches independently for Heavy and Light chains so you may want to build two databases.

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