Peptide generation from the identified mutations
I have identified SNPs using bioinformatics analysis and now I want to generate peptides for the identified SNPs. These SNPs are in huge number ~10000. How to do this? Are there any software/ tools available?
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Rucha.Wadapurkar •
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Rucha.Wadapurkar •
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Hi! Welcome to Biostars :). Maybe you can take a look to these two links for some guidance and inspiration: How to get the mutated protein sequence from the DNA mutation information like the VCF or MAF file? and Generate peptide sequences from VCF . Personally, I have used Haplosaurus from VEP to reconstruct the mutated protein sequences, followed by a small custom script running sliding window of the desired peptide length.