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z score in gene expression data

Hi

I have a matrix like this. Which contains in rows gene names and in column sample ID. In each cell, we have the z score. And the data are related to cancer patients. Now I want to know how can I understand if a gene is up-regulated or down-regulated in our condition. Is there any specific package and command in R to achieve this aim? Or can I simply take the average of each row to get the unique z score for each gene?

Thanks in advance for all your suggestions.

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expression z-score

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