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PRS with multiple panels of SNP weights

Hi everyone,

I would like to estimate the Polygenic risk score with multiple SNP weight panels, do you know what is the most efficient way to do that?

I tried with PLINK(2) but it seems each time, we will need to read the genotype file again which is time-consuming.

Thank you very much!

prs
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written by landscape95 landscape95

1 answer

PLINK2 accepts a multicolumn file, where each column corresponds to a different set of SNP weights.

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written by chrchang523 chrchang523

Thanks you very much Christopher!

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written by landscape95 landscape95

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