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Application of repeated measurement data to missForest

I am considering applying missForest R package to proteome data from mass-spectrometry. This data was measured twice before and after treatment on 20 subjects. I understand that missForest requires observables that are pairwise independent. Can't such repeatedly measured omics data be applied to missForest? I would be grateful if you could enlighten me.

r missforest

1 answer

I was able to get an answer from the developer on this issue. I am happy to share the link to the answer here. https://github.com/stekhoven/missForest/issues/28

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