Swiss-prot and pfam
Hi all,
I have a very general question. Is it safe to assume that Pfam has identified (nearly) all functional domains of swiss-prot proteins?
Best,
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no, it is not safe to assume that.
Besides Pfam there are many other DBs with functional (&structural ) domains, that might not be present in Pfam.
On a more positive note, Pfam will hold many many of the functional domains in swiss-prot so in worst case you will miss out only a limited number
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