Are multiple-testing correction required to construct a network using mixOmics to integrate data from two omics?
Hi all, I am now using the mixOmics package to integrate the two omic datasets, the sPLS-DA (sparse PLS-DA) model is executed to test whether a set of variables can distinguish the groups and the similarity values between pair of variables are calculated by the network function. Do multiple-testing correction need during this process?
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lorenzo.campanelli11 •
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xiaoxiao •
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xiaoxiao •
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No because you are doing a exploratory analysis. You will be observing how de variables describe your subjects. You wont be proofing an hypothesis.
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