I am trying to use maftools to analyze some data. I already have two maf files and I could load them into R and analyze both. For each of them, the Tumor_Sample_Barcoad = __UNKNOWN__, and I would like to merge them together. By using these codes, I set their barcode differently:
del@variants.per.sample$Tumor_Sample_Barcode = "del"
wt@variants.per.sample$Tumor_Sample_Barcode = "wt"
Then, follow this post (Here), I merge them together by:
maf = maftools::merge_mafs( maf = c(del,wt), verbose = TRUE)
What I expected is a maf object with two samples (i.e., the barcode with del and wt); however, I got:
maf@variants.per.sample$Tumor_Sample_Barcode
[1] __UNKNOWN__
Levels: __UNKNOWN__
which makes me extremely confused. I tried to save the two maf objects into maf files and merge them using cat:
save(del, file = "del.maf")
save(wt, file = "wt.maf")
cat "del.maf" "wt.maf" > try.maf (linux)
However, it seems that I cannot save a maf object like this (as the file I got is unreadable). Is there any solution to this problem? Thanks a lot!
Session info:
sessionInfo()
R version 4.1.3 (2022-03-10)
Platform: x86_64-apple-darwin17.0 (64-bit)
Running under: macOS Monterey 12.3
Matrix products: default
LAPACK: /Library/Frameworks/R.framework/Versions/4.1/Resources/lib/libRlapack.dylib
locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8
attached base packages:
[1] stats graphics grDevices utils datasets methods base
other attached packages:
[1] maftools_2.10.05
loaded via a namespace (and not attached):
[1] compiler_4.1.3 Matrix_1.4-0 tools_4.1.3 RColorBrewer_1.1-2 survival_3.3-1
[6] splines_4.1.3 grid_4.1.3 data.table_1.14.2 lattice_0.20-45
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