Can someone explain me the concept of genome wide burden testing of rare variants in cases vs controls? Why is it not called running a logistic regression across cases and controls for rare variants counts?
I have a cancer case-control germline DNA sequencing study, 100 cases and 100 healthy controls. I've called my variants, and now I'm looking to filter …
I'm aligning reads for an ATAC project and I get vastly different alignment percentages when running a bowtie --very-sensitive alignment to the HardMasked vs Unmasked …
Hi everyone, I have exome data of 25 unrelated patients and 40 unrelated control samples. I'm looking for rare variants associated with the disease. I've …