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any tool to plot the fragment profile for ctDNA samples?

Hi all,

Fragment size of ctDNA offered us another dimension data, since cfDNA from tumors tended to smaller than normal ones.

As displayed in "Genome-wide cell-free DNA fragmentation in patients with cancer", fig.2 offered me a direct information (or comparison) between normal and tumors.

enter image description here

I am wondering is there any tool to generate such a figure from a single bam or batch of bams?

Thanks, Junfeng

fragment ctdna

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