Fold80 Penalty value vs PCT > 0.2*mean
Hi all, I know that Fold80 Penalty value is defined as the fold of additional sequencing required to ensure that 80% of the target bases achieve the mean coverage, whereas the the percentage of targeted base positions in which the read depth is greater than 0.2 times the mean region target coverage depth. I want to understand which is the best one to use for the analysis or if I need to use both. Thanks
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