Binding site mutation
I have a class project that involves searching literature reviews for the most relevant mutations in RDRP protein in SARS COV-2 and building a 3D model of the mutated protein using SWISS MODEL and then testing a set of ligands provided to us by the professor using AUTO DOCK VINA and writing a paper detailing our findings. So my question is, while the 3d model of the mutant protein doesn't have the original ligand found in the template, can use the binding site of the template in MGLTools ?
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Mohamed Elsherbieny •
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