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topGO : compare 2 distinct groups

Hi !

I have 2 sets of separate genes that have GOterms and that I want to compare using topGO. My problem is that topGO seams only able to compare a set of genes to a "universe" it is included in. Do you know how to compare 2 or more groups with topGO ?

Cheers,

topgo

What exactly you want to compare among them?

Oh, I actually want to see if a set of metagenomic viruses have the same type of goterms essociated to their genes than a set of isolated viruses

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