STRINGdb "Expected Interactions"?
For example, I put in a list of genes, and above the network plot I get these:
proteins:118
interactions: 816
expected interactions: 204 (p-value 0)
Does the "expected interactions" value come from IF you gave it a completely random, uncorrelated set of genes? Is there any further insight from these metrics?
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Mensur Dlakic
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Kind Katydid •
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Kind Katydid •
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Expected interactions are calculated for a set of protein of a given size. See this paper, specifically the STATISTICAL ENRICHMENT ANALYSIS section.
In your case the network members are extremely well-connected, and from the p-value that is unlikely to be by chance.
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