This is a test version of Biostars. For the public version, visit https://www.biostars.org.
Tool to run statistics on a list of genes and output associated conditions/phenotypes that intersect the most?

Hi, I have found a lot of tools that do the opposite, phenotypes to gene list, but if I have a gene list, is there a tool that can output associated phenotypes/conditions most strongly associated with that set of genes? Thanks

phenotypes genes

2 answers

Enrichr check the gene set Human_Phenotype_Ontology

Are you familiar with R?

There is quite a lot tools but my favorite is geneclusterprofiler in bioconductor https://bioconductor.org/packages/release/bioc/vignettes/clusterProfiler/inst/doc/clusterProfiler.html

Vignette is here http://yulab-smu.top/clusterProfiler-book/index.html

Log in to answer this question.