Non-european ancestry in eQTL analysis
What is the best way to deal with non-european ancestry in eQTL analysis?
We have matched RNASeq and genotype data for 85 subjects, 21 of which show evidence of non-european ancestry.
It seems a common approach is to discard such samples, but this seems wasteful. Can this be dealt with by including genotype principal components in the analysis?
Thank you.
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sim.j.baum
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Colari19
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