Thanks but we have not found the usual Helitron discovery tools like HelitronScanner or EA-Helitron to work satisfactorily. If the initial discovery step is not sensitive and specific, then the following classification step is bound to be a waste of time, i.e. garbage in from "discovery" => garbage out after "classification".
Rather than expand on why that is the case, and divert this post, we want to reiterate our question / request from our original post:
Is there anyone here in the bioinformatics community with expertise in using signal processing tools, to evaluate the papers linked in the Google profile, to cross-verify that one or more of these signal processing tool(s) can indeed be used for
- Helitron discovery, and
- Helitron classification.
Thanks!