While reading SWEEP documentation (Sabeti, 2005) for selective sweep analysis on population data, on page 6 there was given genotyped data file format which sweep takes as input e.g.,
1st column shows the individual identifier, 2nd column the chromosome identifier. T shows transmitted and U shows Untransmitted.. Columns 3 – N: each column gives the allele for one SNP in the order of its position on the chromosome. The alleles are represented as A=1, C=2, G=3, T=4.
1331-1331FF12 T 1 3 3 2
1331-1331FF12 U 1 1 1 2
As written in documentation " The first row therefore represents one chromosome for individual 1331-1331FF12 with the haplotype AGAAT. The second row represents the other chromosome for individual 1331-1331FF12 with the haplotype AAGGC." I am unable to understand how 1 3 3 2 and 1 1 1 2 order of SNPs can lead to haplotype AGAAT and AAGGC, respectively. In dire need to understand this point. Thanks.
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I guess you are referring to this file: http://www.broadinstitute.org/mpg/sweep/documentation/Sweep_Documentation_Dec05.pdf . I have looked at it, but honestly, I have no idea. It may be a typo in the documentation?