Entering edit mode
10.7 years ago
symphx92
▴
10
I am designing synthetic ribozymes, and need to see the secondary structure that arises from its flanking arms binding to a target mRNA. I've used Mfold as well as IDT's OligoAnalyzer (Hairpin), but these only allow from prediction of secondary structure of the ribozyme folding on itself (which is thermodynamically less stable that 20-40 perfectly complementary nucleotides along the arms).
Is there any software that will allow for simultaneous prediction of secondary structure of two RNA molecules?