This is a test version of Biostars. For the public version, visit https://www.biostars.org.
Chromatin Conformation Capture Replication Forks

Why does chromatin capture conformation yield anything quantitatively noticeable above replication fork ligation junctions? Surely the outcome of the ligation/religation would be many replication forks and very few (in comparison) informative junctions?

My guess is that the data is filtered to remove replication forks in post-processing, but i'm new to the technique and unclear at this point. Can anyone help? Thanks.

0 answers

No answers yet.

Log in to answer this question.