Hi, I just came across the news that Illumina is preparing 10kb reads on the hiseq in the future. http://investor.illumina.com/phoenix.zhtml?c=121127&p=irol-newsArticle&ID=1772443&highlight=
Quotes: A novel library prep method and analysis algorithm, enabled by the acquisition of Moleculo Inc., will produce synthetic read lengths up to 10 kb at an extremely low error rate (Q50 or better). This advancement allows more comprehensive coverage and accurate genotyping of clinically important genes and new applications such as phased resequencing of human genomes, and rapid de novo sequencing of complex plant and animal genomes.
Does anyone know when it will be available and more importantly, what changes will it make to all the current NGS tools such as alignment, variant calling, etc..? Thanks.