Practical Comparison Of Features Offered By Pathway Analysis Software: Ipa Vs Metacore · Biostar

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Practical Comparison Of Features Offered By Pathway Analysis Software: Ipa Vs Metacore

Hello All,

Can you please ( if available) provide any detail comparison of pathway analyses between IPA and Metacore, I have found some text from web about their features but couldn't find a practical comparison from somebody who has used both. Whether these software pathway analyses are good for cancer or autoimmune gene sets etc.

Thanks in advance, Indrani

pathway

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updated 4.5 years ago by Ram

• written 13.5 years ago by indranipoddar •

Hi

Metacore has disease ontologies and annotation. A direct comparison of databases can be found at: http://www.ncbi.nlm.nih.gov/pubmed/21356087. Your analysis is best with a better quality database.

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updated 4.5 years ago by Ram

• written 11.7 years ago by jpleasance •

Yes. What about KEGG and Reactome.

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written 6.7 years ago by Shicheng Guo

1 answer

Such feature wise comparisons probably do not exist, however there are much heterogeneity between databases, so far as interactions or edges are concerned. Check this reference for the extent of edge heterogeneity among databases like GeneGO, Reactome, String, NCI etc. http://www.biomedcentral.com/1752-0509/6/29 http://www.biomedcentral.com/1752-0509/6/29/figure/F4

and you may find this forum post helpful http://www.sharedproteomics.com/forum/showthread.php?402-Ingenuity-Pathway-Analysis%28IPA%29-vs.-GeneGO-Metacore

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written 13.5 years ago by Woa

Thank you for your answer. Indrani

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written 13.5 years ago by indranipoddar •

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