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Example Of Residue Mutation And Related Disease

Hi;

I am looking for a few examples where it has been proved that a mutation of an interface residues in a protein-protein complex has inhibited the binding of the 2 proteins and resulted in a crucial disease.

Do you have any suggestions?

Thanks in advance

mutation interaction
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updated by Biostar Biostar • written by Reyhaneh Reyhaneh

1 answer

Here are a few papers which you may find useful:

http://www.ncbi.nlm.nih.gov/pubmed/22072597

http://www.ncbi.nlm.nih.gov/pubmed/22252508

http://www.ncbi.nlm.nih.gov/pubmed/19888216

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written by cmyates89 • cmyates89

Thanks for these

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written by Reyhaneh Reyhaneh

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