Assessing Conditinal Independence Of Genes In Trans-Eqtl Cluster
Hi,
I've identified a SNP that is associated with a variable of interest (lets just call it height) using a Genome Wide Association Study (GWAS).
I also have gene expression data for the samples and it appears that the SNP is affecting the expression of a large number (~500) genes - a trans-eQTL cluster. I'm wondering if there a convenient statistical package/technique available to assess if the variable (height) becomes independent of genotype conditioning on the expression of each of the genes in the trans-eQTL cluster (i.e. assessing conditional independence of each of the ~500 genes)?
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