For example, here's an instance where there + and -. What do these mean?

M00357

K00925,K00625,K01895,

K00193+K00197+K00194,

K00577+K00578+K00579+K00580+K00581-K00582-K00583+K00584,K00399+K00401+K00402,

K22480+K22481+K22482,

K03388+K03389+K03390,

K08264+K08265,

K14126+K14128,

K14127,

K22516+K00125

What does it all mean, Bazel? If I want to find all the orthologs in a particular module do I just remove the + and - or is it much more complicated than that?