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identify most variable bacteria within microbiome longitudinal data

Hello everyone,

I have a theoretical questions: which would be the best analysis to highlight which bacteria species have the greatest variability in relative abundance using longitudinal data? I have found several tutorial but nothing that identify (with a statistical significane) which are the bacteria species that change more their abundance across different samples on longitudinal data? I have a dataset with several replicates belonging to different time point, I would like to understand which are the species that have the deepest changes in their abundance across all the time points. Does anyone have any suggestions about? thanks

microbiome longitudinal data statistics r

I think the "everything is everywhere but the environment selects" hypothesis describes bacterial biogeography rather well. In addition, I don't believe that bacterial species really even exist..

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