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What is the difference between differential isoform usage and isoform switch?

Hi All,

What is the difference between isoform usage and isoform switching? What is the biological difference between this two term? What I understand isoform usage is calculated based on isoform fraction per sample whereas isoform switch is an event where isoforms of same gene is differentially expressed. But I cant find what different independent biological questions can be answered by the individual events.

Thanks

isoformswitch isoform-usage

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