Hisat2 uses some code from Bowtie2 but makes use of a different
underlying index (first it was a hierarchical FM index, now its a
hierarchical graph FM index) that is more cache friendly than what
Bowtie2 uses (a relatively standard FM index).
Hello! I was wandering what is the difference between Bowtie2 and Hisat2 (not taking into account the algorithm). What tool should I use depending on …
Hi everyone, I'm having some troubles with the indexing of the reference genome (GRCh38) with 'bowtie2-build': bowtie2-build ReferenceGenome GRCh38_index --large-index The indexes I've build (by …
Greetings, what is the difference between the prebuilt HISAT2 indexes grch38.tar.gz and grch38_snp.tar.gz found [here?][1] The [readme file][2] is not very clear, at least to …
Hi everybody, Somebody knows which is the difference between GRCM38 and mm10 genomes? There are both [HISAT2][1] indexes. Which is the difference? Thanks [1]: https://ccb.jhu.edu/software/hisat2/manual.shtml