This is a test version of Biostars. For the public version, visit https://www.biostars.org.
GO enrichment based on own DEG and GO annotation

Hello, In my RNAseq project I have generated DEG results by Deseq2 and I have a GO annotation dataframe (gene id with GO numbers), so it`s not a model organism. I was starting to analyze GO enrichment with TopGo, which worked well and I have a lot of enriched GO terms. But to get a better overview, I would like to plot them, preferred as barplot of up-regulated and down-regulated genes (probably separate for Biological Process, Molecular Function, Cellular Component) to get a better overview. Also it would make sense to assign them to categories, such as reproduction, metabolic....

I know there a lot of packages for Rstudio available but mainly usable for model organisms and they use public online annotation databases.

Can you recommend any package, script, vignette for using a custom annotation?

Thanks a lot!

go enrichment deg rna-seq

0 answers

No answers yet.

Log in to answer this question.