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Simulation study to compare the power of different approaches

Hi,

I am working on case-control study, rare variants are focus. For Rare-Variant Association Testing I used SKAT-O and GenePy.

I would like to perform simulation study to compare the power of these two approaches. Ideally, I would like to generate SNP data for around 1000 samples for cases and 1000 for controls for about 15 genes. What do you suggest?

Thanks!

ngs simulation study rare variants

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