Beta calculation for SNPs in PLINK
Hi,
How is Beta calculated in PLINK, as I have three genotypes AA, AB, and BB of one SNP and I have the average of blood pressure of each genotype?
Thank you in advance
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1 answer
If I remember correctly, the beta is generated via linear regression, with the genotype coded as 0, 1 and 2. If there is no covariate, then the beta is basically obtained by
Phenotype ~ Genotype
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