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hsmetrics on_target_bases and on_baits_bases calculation

Hi there,

I was wondering if anyone knows of the formula used for HSmetrics' ON_BAIT_BASES and ON_TARGET_BASES. I did a quick run using the HSmetrics tool, while inputing the same bed file for both bait and target intervals. The results show that ON_BAIT_BASES and ON_TARGET_BASES are different even though the bedfiles are the same. Does anyone know why this is the case?

Thanks for the help!

hsmetrics hybridization selection

1 answer

Hope, this will be helpful!

https://github.com/broadinstitute/picard/issues/476

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