Sample size calculation for GWAS?

I want to calculate sample size to achieve certain amount of power for GWAS? We are not using any case/control, it is a discrete data.

Would you please recommend which software can do this job? or any paper?

snp r genome gwas genetics

• 1,186 views • link

written 6.0 years ago by bha

0 answers

No answers yet.

More posts like this

Calculation of λ1000 for a continuous trait
written 4.1 years ago by Apprentice

I would like to calculate λGC adjusted to a sample size of 1000 (λ1000) for a continuous trait to assess the inflation of the test …
GWASpower calculation
written 5.0 years ago by putty •

Dear All, Sorry , sounds like a stupid question but been struggling with this for a while. I am trying to do post-hoc power calculation …
Up-to-date GWAS Power Calculator and GWAS power comparison
written 5.3 years ago by moxu

I have used two different methods to do a height GWAS, and would like to know which method has more statistical power. I've searched over …
power calculation for case vs tolerant control
written 7.4 years ago by khn

Hello, I previously asked the question, regarding the tools for sample size calculation for GWAS. It seems that the Power and Sample Size Calculation is …
Sample size calculation for GWAS (fixed number of controls)
written 7.6 years ago by khn

Hello I usually calculate sample sizes for GWAS using QUANTO. This time, the number of controls is already decided to 800, so QUANTO is not …
Simulate the sequence data
written 8.3 years ago by bha

I am working on 1000 genome data, as the number of individuals of different population groups are not large enough, and analysis stooped (algorithm not …
Genetic power calculation: how many individuals will survive p-val correction
written 10.1 years ago by epermina •

Hi, I was trying to wrap my mind around the following question we need to answer: given our experimental design, how many individuals in the …
How to estimate the power of association test for small sample size
written 10.3 years ago by MAPK

I am planning to use association tests such as burden test, but I only have a few sample size. Are there any papers/references, beside this …
Software for power analysis in meta-analysis: compute the maximum significance needed by an additio…
written 12.2 years ago by lillo.sim •

<p>I have an association study analysis (GWAS) that does not reach genome-wide significance (max p-value <10E-5), and there is a potential additional sample (so with …
How To Calculate A Sample Size
written 14.5 years ago by Rnda •

<p>this is my first time doing this, so it's a little primitive but i want to know..</p> <p>conducting an experiment, we will pick a sample …