Pathway/Gene set z-score from log2FC
Is there a way to calculate expression of a pathway/gene sets from DE log2fc?. Ie get the directionality of pathway/gene enrichment analysis instead of traditional enrichment p-values from methods such as cluster profiler.
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Vasu
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kvshamsudheen
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kvshamsudheen
1 answer
you can go with fgsea to do Gene set enrichment analysis. check this tutorial DESeq results to pathways in 60 Seconds with the fgsea package
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