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Gene copy number Alteration Interpretation

I am trying to make sense of gene copy number gain for my studies on cancer. I have obtained the results from Purple tool, which provides purity-ploidy estimation for each sample and gene copy number for each sample.

Among the top frequent loss of genes among all samples (15 samples) are POTED,​ etc., which are not convincing though.

I am looking for a good tutorial on gene copy number analysis.

purple cna wgs cancer

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