During my graduate work, I have come across a problem that I do not know how to solve. I would like to know how probable it is for a DNA strand of length N to have two regions of length M that are complementary.
For example, how likely it is that a DNA strand of 100 nucleotides contains two regions of 5 bases that could form intramolecular base-pairs. Additionally, how long does a DNA strand need to certainly ( probability close to 1) contain two such complementary 5 base regions?
I believe this could be solved with combinatorics, but my math is very rusty and I can't seem to find a solution online. I would be extremely grateful if you could assist me with this problem, in any possible way.
0 answers
No answers yet.
Log in to answer this question.
-
How to count the number and proportion of different barcode combinations in DNA sequencing results
written by tulip •
-
how do I generate frame 5 and 6 from the complementary strand?
written by kianamajd45 •
-
Detecting antisense RNA in unstranded RNA-Seq data
written by newbio17
-
Primer sequences after PCR, Assembly and PCR
written by s.kyungyong64 •
-
Analyse a single DNA strand of DNA
written by EFN •
-
Probabilities and statistical significance of a specific kmer frequency
written by arronar
-
Math backbone in biology/genetics?
written by dshulgin
-
PCR annealing analysis
written by Bioinf/Biotech •
-
Quantifying DNA methylation from Bisulfite-Seq Data
written by Ali
-
fuzzy questions about DNA strand
written by mangfu100
